HD Insights: Volume 1

HD Insights: Volume 1

HD Insights Volume 1 (PDF)

November 3rd, 2011 Heather Hare

How Many People Have Huntington Disease?

September 1st, 2011 rtullio By: Emily Fisher and Alicia Semaka There are two ways to answer the question “how many people have Huntington disease (HD)?” The first is by determining the prevalence (i.e., the proportion of a population that has a given condition at a particular point in time), and the second is by determining the incidence (i.e., the
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Highlights from the World Congress on HD

September 1st, 2011 rtullio By: Mahmoud Pouladi, PhD The 2011 World Congress on Huntington’s Disease in Melbourne, Australia, brought together HD clinicians, basic scientists, patients, families, and support groups. Peter Harper and Sarah Tabrizi gave the opening addresses. Peter Harper presented historical highlights of HD, emphasizing the uniqueness of the HD community among other neurodegenerative disease communities. He said the
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Meet the Company

September 1st, 2011 rtullio         VITAL SIGNS NAME: Prana Biotechnology HEADQUARTERS: Parkville, Victoria, Australia STOCK PRICE AS OF 10/05/11: $1.59 52 WEEK RANGE: $1.13-4.50 MARKET CAPITALIZATION AS OF 10/05/11: $42.4 million EMPLOYEES: Approximately 10 Prana Biotechnology’s research is driven by the hypothesis that metal protein attenuating compounds bind transition metals and prevent oligomerization of amyloid proteins
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Research Round-Up

September 1st, 2011 rtullio By: Lise Munsie In the lab. . . Basic research into the biochemical pathways underlying the pathogenesis of HD continues, with the aim of targeting these pathways for drug delivery. PGC1α, which controls many aspects of oxidative metabolism, has been a focus of recent efforts. Martin and colleagues showed that an upstream activator of PGC1α
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Meet the Investigator

September 1st, 2011 rtullio VITAL SIGNS NAME: Sarah Tabrizi CURRENT POSITION: Professor of Clinical Neurology at University College London EDUCATION: PhD Biochemistry University College London, MBChB University of Edinburgh CURRENT HD ACTIVITIES: Dr. Tabrizi is leading efforts in translational medicine. She is lead investigator of the TRACK-HD study that investigates the neurobiology of premanifest and early onset HD and has
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Editor’s Welcome

September 1st, 2011 rtullio Welcome to the first edition of HD InsightsTM! Our mission is to promote, disseminate, and facilitate research in Huntington disease by producing content that will be valuable and informative to the global community of HD researchers in academia and industry. To fulfill this mission, we have assembled a distinguished editorial board, outstanding writers, and a first
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