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Accelerating treatments that

make a difference

for Huntington's disease

Founded in 1993, Huntington Study Group (HSG) is an organization of compassionate professionals dedicated to accelerating treatments that make a difference and to improving the quality of life and outcomes for those impacted by Huntington’s disease (HD) through research, education, and collaboration. We build HD-focused teams of clinical researchers, medical professionals, and sponsors and, together, conduct compliant and pivotal clinical research and trials, share knowledge, and develop innovative treatments for Huntington’s disease.

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HSG 2023 Annual Meeting

Advancing HD Clinical Research

The Huntington Study Group has led 40+ clinical trials and studies, including trials that resulted in the first three and only FDA-approved drugs for the treatment of HD chorea (tetrabenazine, deutetrabenazine, and valbenazine). In addition, HSG developed the Unified Huntington’s Disease Rating Scale (UHDRS®), an invaluable research tool that provides a uniform assessment of the clinical features and the course of HD. HSG currently provides our expertise and knowledge to Enroll-HD, the world’s largest HD observational study.


HSG Members


Credentialed Trial Sites Worldwide


HD Family Participants Enrolled in HSG Studies

Become a Credentialed Site, Investigator, or Coordinator​

The HSG Credentials Committee maintains credentialing standards and policies to ensure sites meet standard qualifications, are trial ready, and agree to uphold HSG’s principles.​

Join a Study or Trial

When you participate in clinical research, you have the ability to actively contribute to science, share your experiences, improve treatments, and help other people impacted with HD.

CRO Services
and Solutions

HSG is the only clinical research organization (CRO) dedicated to the design and execution of trials for Huntington’s disease and other therapeutic areas within our strategic focus.

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Don't miss HSG 2024!

Since 1993, the Huntington Study Group has hosted its annual, internationally recognized forum for training and education of Huntington’s disease researchers, and to share new research findings and treatments with the worldwide community, plus much more!

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HSG Clinical Research, Inc., is a wholly owned for-profit subsidiary of HSG, that benefits HSG and our mission. HSGCR is the world-leading, clinical research organization (CRO) dedicated to the design and execution of trials for Huntington’s disease.

In more than thirty years of existence, HSG has led 40+ studies and clinical trials on HD – more than any other organization in the world – including the first and largest global study of HD patients, as well as the only three FDA-approved treatments for HD symptoms.

Make a Difference – Become an HSG Member!

Our goal for membership is to create a community of engaged and committed professionals in the world’s first and largest collaborative clinical research network in HD. Members share best practices, conduct trials and studies, attend conferences and meetings, and are eligible to participate with other HD thought leaders on committees and working groups as part of a growing ecosystem of credentialed sites.