The 28th Annual Meeting of the Huntington Study Group


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November 4 – November 6, 2021

HSG 2021: UNMASKING HD took place November 4-6, 2021. Plenary, scientific, and research sessions occurred on Thursday and Friday. Our annual Family Day Symposium took place on Saturday. All sessions, including those with Q&A are now accessible on-demand until October 2022.

While we will not gather together this year in person, we have developed an interesting, novel, and innovative program that will be brought to you anywhere you are located. We will once again provide a highly engaging and interactive virtual online meeting using the Intrado platform. HSG 2021: UNMAKSING HD will provide many of the same experiences you are used to — but from the comfort of your home or office. All recorded content and booth spaces remain available for all registrants to access until November 2022!

INTERACTIVE SESSIONS – plenary presentations, panel discussions, with live Q&A sessions sharing the latest in research and treatments.

● An exciting virtual FAMILY DAY SYMPOSIUM for HD families to hear from HD experts and community advocates.


● Virtual NETWORKING LOUNGE to meet up with, engage and collaborate with colleagues, friends, and experts.

● A virtual EXHIBIT HALL to engage with representatives from industry and advocacy.

● An interactive POSTER PAVILION to browse accepted research abstract posters, and engage with poster presenters during scheduled times.


Registration is required to access HSG 2021: UNMASKING HD on-demand Online registration is currently open.

Note: Be sure to set your spam or junk settings to allow registration and reminder emails from the sender and domain


– Family Day Only – Saturday (FREE!)
This package provides access to Saturday content only.

– HSG Credentialed Investigator $100.00 (USD)
This Package provides access to the entire event.

– Advocacy Organization or Non-Profit $150.00 (USD)
This Package provides access to the entire event.

– General registrant – all 3 days $150.00 (USD)
This Package provides access to the entire event.

-Industry/Pharma $500.00 (USD)
This Package provides access to the entire event.

– Students / Residents / Fellows (FREE)
Proof of current status required. Please email to receive the fully discounted rate. This Package provides access to the entire event.


HSG 2021 Plenary Sessions

Thursday, November 4, 2021

All times listed are for U.S. Eastern Standard Time

  • 10:00 am – HSG 2021 Welcome and State of the Union
  • 10:45 am – HSG 2021 Keynote: Challenge of processing and characterizing postmortem human brains to investigate the pathogenesis of Huntington disease (Jean Paul Vonsattel)
  • 11:45 am – HD Insights of the Year (Tyler VanderWeele)
  • 12:15 pm – Inspirational Speaker (Alexandra Drane)
  • 1:15 pm – Visit the Poster Pavilion and Exhibit Hall
  • 1:45 pm – DNA Repair in Huntington’s Disease (Lesley Jones)
  • 2:15 pm – Genetic Counseling for predictive HD testing: expanding access (Kate Foreman)
  • 2:45 pm – Postmortem Brain Imaging in Juvenile Huntington’s Disease (Tim Koscik)
  • 3:15 pm – HSG Studies – myHDstory (Karen Anderson)
  • 3:30 pm – BREAK – check out the Networking Lounge
  • 3:45 pm – HD Innovators Forum with Live Q&A Panel (Neubase, NeuExcell, Ophidian, PTC, Triplet)

Friday, November 5, 2021

All times listed are for U.S. Eastern Standard Time

  • 10:00 am – Evaluation of a long-term physical therapist-led intervention to promote physical activity in Huntington’s disease: results from the PACE-HD study (presented by Monica Busse-Morris, live Q&A with Lori Quinn)
  • 10:30 am – HSG Studies – vUHDRS® (Samuel Frank, Jody Goldstein)
  • 10:45 am – An update from the tominersen clinical development programme (Scott Schobel, Peter, McColgan)
  • 11:00 am – HSG Studies – PROOF-HD (Michael Hayden – Prilenia)
  • 11:30 am – HSG Studies – KINECT-HD (Dietrich Haubenberger – Neurocrine)
  • 12:00 pm – Visit the Poster Pavilion and Exhibit Hall
  • 12:30 pm – HSG Working Group Presentations (Nora Fritz, Lori Quinn, Jamie Adams)
  • 1:30 pm – Peter Como Symposium Platform Presentation (Sara Picó)
  • 2:00 pm – Can we modify HD with Alfy? (Ai Yamamoto)
  • 2:30 pm – Decoding CSF mutant HTT (Doug Langbehn, Steven Smith, Amber Southwell)
  • 3:00 pm – BREAK – check out the Networking Lounge and Sponsor booths
  • 3:15 pm – Clinical Trials Roundup with Live Q&A Panel (Enroll-HD, HDClarity, Novartis, Sage, uniQure, Wave, Vaccinex)
  • 5:15 pm – Closing Remarks

*Agenda, speakers, and times are subject to change. Check back here for updates and posted agenda as we get closer to the event.

HSG 2021 Family Day Symposium
“Come Together… Right Now!”

View/Download the Family Day Flyer

Saturday, November 6, 2021

All times listed are for U.S. Eastern Standard Time

  • 10:00 am – HSG 2021 FAMILY DAY Welcome & Kickoff (Andrew Feigin, Elise Kayson)
  • 10:15 am – Letting the Genie Out of the Bottle (Martha Nance)
  • 10:45 am – Q&A: What’s on Your Mind? (Martha Nance, Andrew Duker, Jee Bang, Jaime Hatcher-Martin)
  • 11:00 am Breakout Session – HD 101 (Andrew Duker)
  • 11:00 am Breakout Session – New and upcoming research in therapeutics (Jee Bang, Wenzhen Duan)
  • 11:00 am Breakout Session – Who is the HSG? (Andrew Feigin, Elise Kayson, Shari Kinel)
  • 11:40 am – Break
  • 11:45 am Breakout Session – Huntington disease – What’s New… and What’s Not (Matt Bower)
  • 11:45 am Breakout Session – Huntington’s Disease: A Complementary & Integrative Approach (Danny Bega)
  • 11:45 am Breakout Session – Meet Jim Gusella!
  • 12:25 pm – Break
  • 12:30 pm Breakout Session – Demystifying behavior in Huntington disease (Katherine McDonell)
  • 12:30 pm Breakout Session – Stand Up and JOIN-HD (Lauren Byrne)
  • 12:30 pm Breakout Session – Meet Victor Sung and Sam Frank!
  • 1:10 pm – Roche Update (Peter McColgan and Lauren Boak, moderated by Jee Bang)
  • 1:30 pm – Research Blitz (Neurocrine – Daniel Claassen, Prilenia – Michael Hayden, uniQure – Erin Furr Stimming, Wave – Ralf Reilmann, Novartis – Blair Leavitt, Sage – Aaron Koenig, HDClarity – Ed Wild)
  • 2:40 pm – Q&A – Ask the Investigators Working on the Trials

*Agenda, speakers, and times are subject to change. Check back here for updates and posted agenda as we get closer to the event.


*NEW THIS YEAR!* Submitted abstracts chosen by the HSG Publications Committee were published in the Journal of Huntington’s Disease.

Click to View Publication

Abstracts must be submitted in accordance with the Journal of Huntington’s Disease Manuscript Submission & Author Instructions Policy. In particular, submitters are asked to adhere to the following. Failure to adhere to the guidelines by result in rejection of your submission:

The abstract for research papers should follow the “structured abstract” format:


The abstract should try to be no longer than 250 words.

Submitters are required to submit the edited abstract in MS Word format (.DOC or .DOCX). A detailed summary of the abstract or full plain text version is also required to be entered or pasted into the appropriate submission portal field.

Authors are requested to use the Vancouver citation style. Place citations as numbers in square brackets in the text. All publications cited in the text should be presented in a list of references at the end of the manuscript. List the references in the order in which they appear in the text. Only articles published or accepted for publication should be listed in the reference list. We discourage textual references to unpublished and unavailable data. With permission, the author can reference a personal communication with name in the discussion section. If an article has a DOI, this should be provided after the page number details. The number is added after the letters ‘doi’. Manuscripts will not be considered if they do not conform to the Vancouver citation guidelines.

Please DO NOT INCLUDE tables, figures, supplementary material, or graphics in your abstract submission. Tables, figures, supplementary materials, and additional graphics may be included in your poster and virtual poster booth configuration.

Attendees will “experience” a virtual poster event that replicates everything the HSG Annual Meeting poster sessions have come to be known for. Abstract posters will be presented in our Virtual Poster Pavilion. Each abstract selected by the HSG Publications Committee will be provided a configurable poster booth that can include a short introductory video, a headshot picture of the presenter, a PDF of the detailed poster and abstract, a Q&A chat box to interact with the poster presenter, and any other relevant reference materials the author or presenter want to include.


– Regular Abstract Submission Closes: July 31, 2021
– Regular Abstract Selection Notification: August 31, 2021
– Late-breaking Abstract Submission: September 1-10, 2021*

*Late-Breaking Abstract Submission period occurs after key print deadlines and will only be eligible to present at a poster booth. Late-breaking abstracts are not included in the online publication of HSG 2021 Abstracts in the Journal of Huntington’s Disease.

Update (September 13, 2021): Abstract submissions are no longer being accepted for HSG 2021: UNMASKING HD.


The Huntington Study Group has updated HSG 2021: UNMASKING HD sponsor and exhibitor packages with some exciting opportunities to maintain a consistent experience as our usual in-person event. Please contact Kristin Strazdins to request our HSG 2021 Sponsor/Exhibitor Packet and book your organization’s presence at this premier annual event!

Kristin Strazdins
Phone (toll-free): 1-800-487-7671

HSG 2021: UNMASKING HD Sponsors

Roche - Genentech


Sage Therapeutics

Teva Pharmaceuticals


PTC Therapeutics

Mitochon Pharmaceuticals

Spark Therapeutics

Wave Life Sciences

Huntington's Disease Youth Organization

HD Reach

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