27th Annual Meeting of the Huntington Study Group


October 29-31, 2020

The Huntington Study Group took the early and proactive step of moving this year’s annual meeting, HSG 2020: HD IN FOCUS, to a virtual experience during October 29-31, 2020. While we will not gather together this year in-person, we have developed an interesting, novel, and innovative program that will be brought to you anywhere you are located.

We held a highly engaging and interactive virtual online meeting using the Intrado INXPO platform. HSG 2020 still provided many of the same experiences you are used to — but from the safety and comfort of your home or office. All recorded content and booth spaces remain available for all registrants to access until October 20201!

INTERACTIVE SESSIONS – plenary presentations, panel discussions, with live Q&A sessions sharing the latest in research and treatments.

● An exciting VIRTUAL FAMILY DAY symposium for HD families to hear from HD experts and community advocates.


● Virtual NETWORKING LOUNGES to meet up with, engage and collaborate with colleagues, friends, and experts.

● A simulated EXHIBIT HALL to engage with representatives from industry and advocacy.

● An interactive POSTER PAVILION to browse accepted research abstract posters, and engage with poster presenters at scheduled times.


This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of PeerPoint Medical Education Institute, LLC and Huntington Study Group. The PeerPoint Medical Education Institute, LLC is accredited by the ACCME to provide continuing medical education for physicians.

For more information on claiming CME credits, please click to review the Accreditation and Designation statements with Disclosure Report.

To obtain your CME Certificate

  • Open your web browser and go to: https://peerptlogin.com
  • Login:
    • Email: your email address
    • Password: Your First Name (case sensitive)
  • Select tab: ‘Complete Surveys and Tests’
  • Click on Post-Test
  • Complete your Post-Test and submit
  • Click on Return to Exam List
  • Click on: Conference description (this will open Survey)
  • Complete your Survey and ‘Save’
  • Select Tab ‘Print CME Certificates’
  • Next to Conference description select: ‘Assign Credit Hours’
  • A window opens stating the maximum number of credit hours for this conference
    • If you attended entire conference, select maximum number of hours from drop-down
    • If you attended less than the entire conference, select the actual number of hours you attended from drop-down
  • Select: ‘Save Credit Hours’
  • Select: ‘View/Print’
  • Depending upon your device: either the CME Certificate PDF will download, or a window opens to download your CME Certificate then select ‘Save File’.


All times listed are in Eastern Standard Time (EST). Times and topics are subject to change.

October 29, 2020 (Thursday) – General Sessions

  • 10:00 am – Welcome and Kickoff
  • 10:10 am – HSG State of the Union
  • 10:45 am – Unstable DNA in Huntington disease: dynamics, consequences and therapeutic opportunities
  • 11:15 am – Genetic Engineering Related to HD Therapeutics
  • 11:45 am – Poster Session/ Exhibit Hall/ Networking Lounge
  • 12:30 pm – Keynote “Zooming In On HD” – Sarah Tabrizi, UCL
  • 1:30 pm – Is Huntington’s Disease Caused by a Malformation of Cortical Development?
  • 1:45 pm – Preparing for clinical trials in Juvenile-Onset Huntington’s Disease
  • 2:00 pm – Poster Session/ Exhibit Hall/ Networking Lounge
  • 2:45 pm – HSG Working Group Presentations
    • Rehabilitation Therapists
    • Digital Therapies
    • Neuropsychology
    • Behavioral
  • 3:15 pm – Peter Como Symposium Platform Presentations
    • Detection of early neurodegeneration with fluid biomarkers in the HD Young Adult Study
    • Optimizing Nanoparticles for Intranasal Administration of Gene Therapy of Huntington’s Disease
  • 3:45 pm – myHDstory
  • 4:15 pm – HD Innovators Forum
    • Triplet Therapeutics
    • NeuExcell Therapeutics
    • Mitochon Pharmaceuticals
    • Neubase Therapeutics
  • 5:30 pm – 8:00 pm: Networking

October 30, 2020 (Friday) – General Sessions

  • 10:00 am – Results of the SIGNAL Trial Evaluating the Safety and Efficacy of Pepinemab in Huntington’s Disease
  • 11:00 am – Physical and occupational therapy in Huntington’s Disease: Promoting evidence-based interventions and new models of care
  • 11:30 am – MCI and Dementia in Motor-manifest HD
  • 12:00 pm – Clinical Behavioral Changes in early Huntington’s Disease
  • 1:00 pm – Poster Session/ Exhibit Hall/ Networking Lounge
  • 1:15 pm – Clinical Trial Round Up Part 1; Ongoing Trials
    • Prilenia: The PROOF-HD Study: PRidopidine’s Outcome On Function in Huntington Disease
    • Wave: Update on Allele-Selective Approach to Huntington’s Disease
    • uniQure: Updates on HD-GeneTRX-1: A phase 1-2 clinical trial of CNS-administered gene therapy (AMT-130) for early stage HD
    • Annexon: Phase 2a Study of ANX005, a Humanized anti-C1q mAb, in Patients with Huntington disease
    • Neurocrine: Clinical Trial Update: Valbenazine for the Treatment of Chorea in Huntington Disease
    • Roche: An Update from the Tominersen Global Clinical Development Programme
  • 2:45 pm – Clinical Trial Round Up Part 2; What’s Coming?
    • Sage: Understanding Executive Functioning in HD
    • Azevan: Developing SRX246 for Irritability and Aggression in Huntington’s Disease
    • Novartis: Branaplam: Mechanism of action and clinical development plans for an oral HTT lowering compound
  • 3:45 pm – HD-NET
  • 4:15 pm – HD Insights of the Year: “Factor-H: strengthening communities afflicted by HD in Latin America”
  • 5:15 pm – Closing Remarks
  • 5:30 pm – 8:00 pm: Networking

October 31, 2020 (Saturday) – FAMILY DAY

  • 12:00 pm – Welcome
  • 1:00 pm – Breakout sessions
    • “I’m under 30 and I don’t have symptoms of HD”
      • 1:10 pm – Growing Up in an HD Family – Child Caregiving, Being At-Risk, Support for Kids
      • 1:45 pm – Impact of Being At-Risk on Big Decisions – Testing or Not, Marriage, Job, Reproduction
      • 2:20 – New Ideas/Tools for Research, Advocacy, Living Life Better
    • “HD is Here Today and I Have to Deal With It”
      • 1:10-1:40 – Why You Need a Team and How to Build One
      • 1:45-2:15 Planning for the Future—Financial and Medical Care Planning
      • 2:20-2:50 – New Ways to Address Behavioral Challenges
    • “Time is Passing”
      • 1:10-1:40 Living Well in the Later Stages of Life and the Later Stages of HD
      • 1:45-2:15 Death and Dying
      • 2:20-2:50 – “Put Your Own Mask on First Before Assisting Others”- Caring for Yourself as You Care for Someone Else
  • 2:50 pm – Beak/Poster Session/ Exhibit Hall/ Networking Lounge
  • 3:10 pm – Ask the Experts Panel
  • 3:45 pm – HD Research Blitz
    • PRECISION-HD: Allele-Selective Targeting of Mutant HTT
    • KINECT-HD: Valbenazine for the Treatment of Chorea in Huntington Disease
    • SIGNAL Update
    • Roche HD studies: HD Natural History Study, GENERATION HD1, and the GEN-EXTEND trial
  • 4:45 pm – Round Up and Closing Remarks

Venue & Registration

Registration for enduring content is still available!
(note: attendees that registered and/or attended the live event can continue to access the content until October 2021)

Abstracts and Virtual Poster Sessions

Attendees will “experience” a virtual event that mimics a similar live event. Abstract posters will be presented in a dedicated virtual exhibition hall. Once in the Poster exhibition hall, attendees will see the titles and a thumbnail image for each selected abstract. When an attendee navigates to a specific poster, they will be presented with an interface that can include a short introductory video, a headshot image of the presenter, a PDF to view the detailed poster, and a Q&A chat box to interact with the poster presenter.

This year, the HSG Publications Committee has accepted over 100 regular abstract submissions for HSG 2020: HD IN FOCUS. You can view the accepted abstract list and Poster Presenters.

The submission periods for abstracts are now complete and the submission portal is closed.

Key Abstract Dates:

– Regular Abstract Submission Opens: May 28, 2020
– Regular Abstract Submission Closes: June 30, 2020
– Regular Abstract Selection Notification: August 31, 2020
– Late-breaking Abstract Submission: September 9-16, 2020*

*Late-Breaking Abstract Submission period will take place after key print deadlines, and therefore cannot be included in the publication of HSG 2020 Abstracts in Neurotherapeutics®. Poster presenters will still be welcome.

NEW: Disclosures for authors are REQUIRED in order to submit an abstract. Please be sure to obtain disclosures for authors prior to beginning your submission.

Abstract Guidelines

HSG 2020 Sponsorship Opportunities

The window for new sponsorships to appear in meeting images or announcements, or not request an exhibitor booth is now closed.

For HSG 2020: HD IN FOCUS, the Huntington Study Group has updated sponsor packages with some exciting opportunities to maintain a consistent experience as our usual in-person event.

Download the HSG 2020 Detailed Sponsorship Packet.

Please contact Kristin Strazdins (kristin@hsglimited.org or 585.242.0967) for any questions regarding sponsorship.

HSG 2020 Sponsors

Thank you to all the sponsors of HSG 2020: HD IN FOCUS for helping make our annual meeting a (virtual) reality! We invite you to visit them at the annual meeting and learn more about what they are doing.

Gold Sponsor

Silver Sponsors

Bronze Sponsors

Friend Sponsors



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