HSG 2019: Navigating HD

HSG 2019 Overview

HSG 2019: Navigating HD brought over 700 of the world’s leading Huntington disease (HD) researchers, health care providers, industry representatives, and members of the HD community to navigate the latest in research findings and treatments for HD.

Photos from HSG 2019

Please check back soon for photos from HSG 2019: Navigating HD.

HSG 2019 Agenda and Presentations


8:00 am – 9:45 amWelcome & Introductions
HSG State of the Union
Presentation Not Available for Download
9:45 am – 10:15 amFEATURED SESSION: Meeting Keynote (Martin Graham, PhD)
New Paradigms in Drug Discovery & Development:
Bridging the Gap Between Academia and Industry
10:15 am – 11:00 amFEATURED SESSION: HD Insights of the Year
11:15 am – 12:00 pmFEATURED SESSION: Patient Reported Outcomes – Quality of Life for End of Life (Carlozzi)
12:00 pm – 1:30 pmBuffet Lunch / Exhibitor Hall
12:10 pm – 1:30 pmHSG Working Groups
1) Wearables & Sensors
2) JHD
3) Behavioral
4) Biomarkers
5) Neuropsychology
6) Genetics
1:35 pm – 2:35 pmFEATURED SESSION: An Introduction to Intrathecal Drug Delivery for Huntington’s Disease (Leavitt, Guttman, Bang)
Session Underwriting By:
2:35 pm – 3:40 pmFEATURED SESSION: Panel – Combination Drug Products for HD (Kieburtz, Zauderer, Frank, Podskalny, Fox, O’Brien, Hung)FDA Presentation Not Available for Download
4:00 pm – 5:00 pmPARALLEL SESSION 1: Implications of Genetic Modifiers of HD Trajectory (Gusella, MacDonald)
4:00 pm – 5:00 pmPARALLEL SESSION 2: Panel – To Know or Not to Know: Helping Young Adults Begin Their Journey with HD (Nance, Swope, Daley, Sifry-Platt)
5:00 pm – 5:30 pmPeter Como HD Symposium Poster Viewing
5:35 pm – 6:25 pmFEATURED SESSION: The Role of Brain Development in Huntington’s Disease (Nopoulos)
6:30 pm – 8:30 pmEvening Activities: HSG Awards, Memorials, and Reception


8:30 am – 8:45 amHSG 2019 Host Site Welcome & Introductions (Wheelock, UC Davis)
8:45 am – 10:15 amFEATURED SESSION: Panel – Exploring Novel HD Assessment Tools (Seeberger, Ross, Stebbins, Fuller, Heatwole, Shoulson)
10:15 am – 11:30 amSIGNAL TRIAL (Closed Session – by invitation only)
11:30 am – 12:30 pmBuffet Lunch/Exhibitor Hall
11:30 am – 12:30 pmPARALLEL SESSION: HSG 2019 Working Group Presentations
12:30 pm – 1:15 pmFEATURED SESSION: Intracranial Gene Therapy for Neurodegenerative Disorders (Larson)
Session Underwriting By:
1:15 pm – 3:15 pmFEATURED SESSION: HD Innovators Forum (Ross, Leavitt)
Prilenia, MC10, Sage Therapeutics, Annexon, Novartis
Sage Therapeutics Presentation Not Available for Download
3:15 pm – 4:15 pmPeter Como HD Symposium Poster Viewing
3:40 pm – 4:00 pmHSG 2019 Gold Sponsor Scientific Session (Jeffrey Long, PhD)
Challenges in the Design of Premanifest HD Trials
4:15 pm – 5:30 pmFEATURED SESSION: Peter Como HD Symposium Platform Presentations
5:30 pm – 6:00 pmFEATURED SESSION: Research Round-Up
6:00 pmHSG 2019 Wrap-Up


Family Day

10:00 am – 4:00 pmFamily Day

New at HSG 2019

Inaugural HSG Investigator/Coordinator Workshop

The HSG Member Education Committee was established in 2019 to advance the knowledge of our membership through educational training, and to promote clinical trial-ready sites. We were excited to have provided the inaugural full-day training workshop, Investing in the Future – Training Tiger Team Sites on Wednesday, prior to the HSG 2019 general sessions.

We thank all of our session presenters, including Jody Goldstein, Patric Donaghue, Mike Lentine, Anne Van Dusen, Amy Chesire, Jody Corey-Bloom, Andrew Feigin, Samuel Frank, Sandra Kostyk, Julie Stout, Joan Adamo, Richard Dubinsky, Carolyn Gray, Jamie Adams, Emma Waddell, and Karen Anderson.

Support for the session was generously provided by: University of Rochester Medical Center (Elise Kayson), University of California San Diego (Jody Corey-Bloom), Hereditary Neurological Disease Centre (Greg Suter), Georgetown University (Karen Anderson), The Ohio State University (Sandra Kostyk), UT Health McGovern Medical School (Erin Firr Stimming), an anonymous HD family donor, and anonymous Investigator and Coordinator donor.

HSG 2019 Scholarship Winners

The HSG is committed to helping support participation to the maximum extent possible by offering a variety of scholarships that help to cover some portion of costs to attend the annual meeting. The HSG was pleased to recognize the following scholarship winners for HSG 2019: Navigating HD:

Shoulson Scholars

Paula Dietrich, PhD (University of Tennessee)
Natalia Rocha, PharmD, MSc, PhD (UTHealth Houston)

Peter Como Scholar

Sarah Gunn, MSc (University of Leicester)

New Member Scholarships

Cynthia Poon (Northwestern University)
Zhen-Yi Andy Ou (University College London)
Meredith Pauly (University of Pennsylvania)
Muhammad Waseem Anjum (Georgetown University)
Tyler Orem (University of Alabama)
Debbi Fox-Davis (HD Reach)
Charlene Hudson (HD Reach)
Will Tanigaki (UTHealth Houston)

Coordinator Scholarships

Jennifer Klapper (University of Pennsylvania)
Kate Greenly (Rocky Mountain Movement Disorders)

CME4HD Scholarships

The HSG wishes to thank the Griffin Foundation for their generous funding support for HSG 2019 CME4HD scholarships.

Rasheda El-Nazer
Venka Veerappan
Joyce Macedo de Silva
Emmanuel Akano

HSG 2019 Abstracts

The HSG Publications accepted 107 abstracts for publication and presentation as part of HSG 2019: Navigating HD. Thank you to all who submitted their work for review and consideration. We are honored to help share and publicize your work in HD!

All accepted abstracts were published in the journal Neurotherapeutics. This year, the publisher has provided complimentary access to the online publication. You can access the HSG 2019 abstracts online by:
1. Using the following link – https://link.springer.com/article/10.1007/s13311-019-00788-3
2. By downloading the HSG 2019 Abstract Publication Guidebook using the button below

HSG Thanks Our 2019 Sponsors!

Gold-Level & Family Day Sponsor

Bronze-Level Sponsors

Friend of HSG Sponsors

Supporting Sponsors